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ERRγ agonist-1
ERRγ agonist-1
ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1].
Catalog No. T60772
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ERRγ agonist-1
Catalog No. T60772
ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1].
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose. | Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 25 mg | $1,520 | 10-14 weeks | |
| 50 mg | $1,980 | 10-14 weeks | |
| 100 mg | $2,500 | 10-14 weeks |
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| Description | ERRγ agonist-1 can be used in neuropsychological disorders research. ERRγ agonist-1 increases the ERRγ transcriptional activities that is a potent agonist of ERRγ [1]. |
| In vitro | ERRγ agonist-1 (Compound 5d), at a concentration of 5 μM over three days, significantly enhances the expression of markers for dopaminergic neuron phenotype, namely tyrosine hydroxylase (TH) and dopamine transporter (DAT), in SH-SY5Y neuroblastoma cells [1]. This elevation in dopaminergic markers is attributed to ERRγ agonist-1's activation of the CREB-signaling pathway, leading to an induction of dopaminergic neuronal phenotypes. Western Blot analysis confirms the increased levels of TH and DAT in SH-SY5Y cells under these conditions [1]. |
| Molecular Weight | 311.38 |
| Formula | C17H21N5O |
| Cas No. |
| Storage | Shipping with blue ice. |
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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