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Etofylline clofibrate

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Etofylline clofibrate

Catalog No. T15256Cas No. 54504-70-0

Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.

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Pack Size	Price	Availability
2 mg	$48	5 days
5 mg	$76	5 days
1 mL x 10 mM (in DMSO)	$107	5 days

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Product Introduction

Bioactivity

Description	Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.
In vivo	Etofylline clofibrate administered orally at a dosage of 12 mg/kg demonstrates a moderate initial efficacy with a 12% reduction in disaggregation time from a single dose. The effectiveness of the compound increases significantly with consistent daily usage, achieving a maximum reduction in disaggregation time of 31% after 5 days and 43% after 7 days of consecutive applications.

Chemical Properties

Molecular Weight	420.85
Formula	C19H21ClN4O5
Cas No.	54504-70-0

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 52 mg/mL (123.56 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3761 mL	11.8807 mL	23.7614 mL	118.8072 mL
5 mM	0.4752 mL	2.3761 mL	4.7523 mL	23.7614 mL
10 mM	0.2376 mL	1.1881 mL	2.3761 mL	11.8807 mL
20 mM	0.1188 mL	0.5940 mL	1.1881 mL	5.9404 mL
50 mM	0.0475 mL	0.2376 mL	0.4752 mL	2.3761 mL
100 mM	0.0238 mL	0.1188 mL	0.2376 mL	1.1881 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Etofylline clofibrate