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Pack Size | Price | Availability | Quantity |
---|---|---|---|
250 μg (2.31 mM * 500 μL MeOH/NH4OH(70:30) | $170 | 35 days | |
500 μg (2.31 mM * 500 μL MeOH/NH4OH(70:30) | $325 | 35 days | |
1 mg (2.31 mM * 500 μL MeOH/NH4OH(70:30) | $590 | 35 days | |
5 mg (2.31 mM * 500 μL MeOH/NH4OH(70:30) | $2,670 | 35 days |
Description | Farnesyl Pyrophosphate ammonium (Farnesyl diphosphate ammonium) is a metabolic intermediate of the MVA pathway that acts as a newly identified danger signal to trigger acute cell death and induce neuronal loss in stroke. |
In vitro | METHODS: B cell line A20 cells, mouse mastocytoma cell line P815, Jurkat T cell line, primary splenocytes, and primary thymocytes were treated with farnesyl pyrophosphate (15 μg/mL and 30 μg/mL) and the nuclear and plasma membranes were stained to capture morphological changes after FPP treatment by confocal microscopy. RESULTS: Within 5 minutes of adding farnesyl pyrophosphate, P815 cells began to show cytoplasmic swelling that increased over time until the plasma membrane eventually ruptured. [1] |
Alias | FPP ammonium, Farnesyl diphosphate ammonium, (E,E)-Farnesyl pyrophosphate ammonium |
Molecular Weight | 433.42 |
Formula | C15H37N3O7P2 |
Cas No. | 116057-57-9 |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | Methanol:NH4OH (70:30): 1 mg/ml |
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