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FFN 102 mesylate

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Catalog No. T41194Cas No. 1883548-92-2

FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopamine transporters (DAT) and VMAT2.

FFN 102 mesylate

FFN 102 mesylate

🥰Excellent
Purity: 98.81%
Catalog No. T41194Cas No. 1883548-92-2
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopamine transporters (DAT) and VMAT2.
Pack SizePriceAvailabilityQuantity
1 mg$30In Stock
5 mg$67In Stock
10 mg$101In Stock
25 mg$173In Stock
50 mg$247In Stock
100 mg$358In Stock
200 mg$497In Stock
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Purity:98.81%
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Product Introduction

Bioactivity
Description
FFN 102 mesylate is a pH responsive fluorescent false neurotransmitter (FFN), a selective dopamine transporter (DAT) and VMAT2 substrate. Exhibits no significant binding to a panel of 38 CNS receptors, including dopamine and serotonin receptors. Inhibits dopamine uptake. Excitation maxima are 340 nm at pH 5 and 370 nm at pH 7.5. Emission maximum is 435 nm at both pH 5 and 7.5.FFN 102 mesylate is a Ph-responsive fluorescent pseudoneurotransmitter (FFN) that acts as a substrate for selective dopamine transporters (DAT) and VMAT2.
In vitro
The absorption spectra of FFN102 exhibited pH dependence: the absorption maximum shifts toward 331 nm at lower pH values and to 371 nm at higher pH values, corresponding to the protonated and deprotonated forms, respectively [1].
Chemical Properties
Molecular Weight335.76
FormulaC12H14ClNO6S
Cas No.1883548-92-2
SmilesO=C1OC=2C=C(O)C(Cl)=CC2C(=C1)CCN.O=S(=O)(O)C
Storage & Solubility Information
Storagekeep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 45 mg/mL (134.02 mM), Sonication is recommended.
H2O: 6.0 mg/mL (18.0 mM), Sonication is recommended.
Solution Preparation Table
H2O/DMSO
1mg5mg10mg50mg
1 mM2.9783 mL14.8916 mL29.7832 mL148.9159 mL
5 mM0.5957 mL2.9783 mL5.9566 mL29.7832 mL
10 mM0.2978 mL1.4892 mL2.9783 mL14.8916 mL
DMSO
1mg5mg10mg50mg
20 mM0.1489 mL0.7446 mL1.4892 mL7.4458 mL
50 mM0.0596 mL0.2978 mL0.5957 mL2.9783 mL
100 mM0.0298 mL0.1489 mL0.2978 mL1.4892 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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