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FGFR4-IN-6

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Catalog No. T64015

FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.

FGFR4-IN-6

FGFR4-IN-6

😃Good
Catalog No. T64015
FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
FGFR4-IN-6 is a covalent, reversible FGFR4 inhibitor (IC50: 5.4 nM) that exhibits good oral pharmacokinetic properties. In a xenograft mouse model of the Hep3B2.1-7 HCC cell line, FGFR4-IN-6 was able to significantly induce tumour regression without significant toxicity.
Chemical Properties
Molecular Weight567.64
FormulaC31H33N7O4
Storage & Solubility Information
StorageShipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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