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Fitusiran

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Catalog No. T38986Cas No. 1499251-18-1
Alias SAR439774, ALN-AT3SC

Fitusiran (ALN-AT3SC) is a small interfering RNA compound designed to selectively bind to antithrombin (AT) messenger RNA in the liver, leading to decreased AT production. By doing so, Fitusiran enhances thrombin generation, making it a promising candidate for hemophilia research.

Fitusiran

Fitusiran

😃Good
Catalog No. T38986Alias SAR439774, ALN-AT3SCCas No. 1499251-18-1
Fitusiran (ALN-AT3SC) is a small interfering RNA compound designed to selectively bind to antithrombin (AT) messenger RNA in the liver, leading to decreased AT production. By doing so, Fitusiran enhances thrombin generation, making it a promising candidate for hemophilia research.
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Product Introduction

Bioactivity
Description
Fitusiran (ALN-AT3SC) is a small interfering RNA compound designed to selectively bind to antithrombin (AT) messenger RNA in the liver, leading to decreased AT production. By doing so, Fitusiran enhances thrombin generation, making it a promising candidate for hemophilia research.
AliasSAR439774, ALN-AT3SC
Chemical Properties
Cas No.1499251-18-1
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

SAR 439774SAR-439774Fitusiran
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