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FLT3-IN-14

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Catalog No. T63058Cas No. 2620551-45-1

FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.

FLT3-IN-14

FLT3-IN-14

😃Good
Catalog No. T63058Cas No. 2620551-45-1
FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.
Pack SizePriceAvailabilityQuantity
25 mg$1,520 8-10 weeks
50 mg$1,980 8-10 weeks
100 mg$2,500 8-10 weeks
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Product Introduction

Bioactivity
Description
FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.
Chemical Properties
Molecular Weight472.56
FormulaC25H24N6O2S
Cas No.2620551-45-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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