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FLT3/ITD-IN-3

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Catalog No. T62824Cas No. 2489446-47-9

FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, demonstrating efficacy against FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM), and FLT3-ITD (IC50: 0.9 nM). It significantly inhibits FLT3 phosphorylation and effectively suppresses the proliferation of AML cells.

FLT3/ITD-IN-3

FLT3/ITD-IN-3

😃Good
Catalog No. T62824Cas No. 2489446-47-9
FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, demonstrating efficacy against FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM), and FLT3-ITD (IC50: 0.9 nM). It significantly inhibits FLT3 phosphorylation and effectively suppresses the proliferation of AML cells.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
FLT3/ITD-IN-3 (Compound 19) is a potent inhibitor of FLT3-ITD, demonstrating efficacy against FLT3D835Y (IC50: 0.3 nM), FLT3 (IC50: 0.4 nM), and FLT3-ITD (IC50: 0.9 nM). It significantly inhibits FLT3 phosphorylation and effectively suppresses the proliferation of AML cells.
Chemical Properties
Molecular Weight455.94
FormulaC22H26ClN7O2
Cas No.2489446-47-9
Storage & Solubility Information
StorageShipping with blue ice.

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