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Fluc-IN-1

Name: Fluc-IN-1
Brand: TargetMol
SKU: T203010
Rating: 4.5 (1 reviews)

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Catalog No. T203010Cas No. 2940242-10-2

Fluc-IN-1 is a potent inhibitor of firefly luciferase (Fluc) (IC 50 = 25 nM) and further inhibits WNT/β-catenin through Fluc (IC50 ≈ 30 nM) without acting through Frizzled 7 or the WNT/β-catenin signaling amplifier.

Fluc-IN-1

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Catalog No. T203010Cas No. 2940242-10-2

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Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	473.61
Formula	C₂₆H₂₃N₃O₂S₂
Cas No.	2940242-10-2
Smiles	O=C(NC1=CC=C(SCC(=O)NC2=NC(=CS2)C=3C=CC=CC3)C=C1)C4=CC=C(C=C4C)C
Relative Density.	no data available

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100.00 mg/mL (211.14 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.1114 mL	10.5572 mL	21.1144 mL	105.5721 mL
5 mM	0.4223 mL	2.1114 mL	4.2229 mL	21.1144 mL
10 mM	0.2111 mL	1.0557 mL	2.1114 mL	10.5572 mL
20 mM	0.1056 mL	0.5279 mL	1.0557 mL	5.2786 mL
50 mM	0.0422 mL	0.2111 mL	0.4223 mL	2.1114 mL
100 mM	0.0211 mL	0.1056 mL	0.2111 mL	1.0557 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

FlucIN1