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Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | Fludarabine triphosphate (F-ara-ATP) trisodium, the principal metabolite of Fludarabine, is a potent, noncompetitive, and specific inhibitor of DNA primase with an IC50 value of 2.3 μM and a Ki of 6.1 μM. It obstructs DNA synthesis by hindering DNA primase and primer RNA formation, while also inhibiting ribonucleotide reductase and DNA polymerase activities, effectively inducing cellular apoptosis [1] [2]. |
Molecular Weight | 591.12 |
Formula | C10H12FN5Na3O13P3 |
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