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Fodipir

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Catalog No. T19327Cas No. 118248-91-2
Alias DPDP

Fodipir, the active metabolite of mangafodipir, plays a crucial role in the mechanism of mangafodipir-mediated cytoprotection, specifically mitigating cell death induced by 7β-hydroxycholesterol.

Fodipir

Fodipir

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Catalog No. T19327Alias DPDPCas No. 118248-91-2
Fodipir, the active metabolite of mangafodipir, plays a crucial role in the mechanism of mangafodipir-mediated cytoprotection, specifically mitigating cell death induced by 7β-hydroxycholesterol.
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2 mg$305 days
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Product Introduction

Bioactivity
Description
Fodipir, the active metabolite of mangafodipir, plays a crucial role in the mechanism of mangafodipir-mediated cytoprotection, specifically mitigating cell death induced by 7β-hydroxycholesterol.
In vitro
Fodipir (Dp-dp; Dipyridoxyl diphosphate; 100 μM) demonstrates significant cytoprotective effects, effectively mitigating 7β-hydroxycholesterol (7β-OH)-induced cell death after 8 hours of treatment. It not only reduces cellular reactive oxygen species (ROS) production triggered by 7β-OH but also inhibits lysosomal membrane permeabilization (LMP), enhancing cell survival. Fodipir, as a principal metabolite of mangafodipir, plays a crucial role in the cytoprotection conferred by mangafodipir against 7β-OH-induced cytotoxicity.
AliasDPDP
Chemical Properties
Molecular Weight638.46
FormulaC22H32N4O14P2
Cas No.118248-91-2
Relative Density.1.657 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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