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Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $367 | 6-8 weeks | |
5 mg | $793 | 6-8 weeks | |
10 mg | $1,090 | 6-8 weeks | |
25 mg | $1,630 | 6-8 weeks | |
50 mg | $2,190 | 6-8 weeks | |
100 mg | $2,960 | 6-8 weeks |
Description | Folate-PEG3-azide is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 641.64 |
Formula | C27H35N11O8 |
Cas No. | 1313026-32-2 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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