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Frondoside A

Frondoside A
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Frondoside A

Catalog No. T11325Cas No. 127367-76-4
possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa,
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Product Introduction

Bioactivity
Description
possesses anticancer, anti-invasive, anti-metastasis, anti-angiogenic and pro-apoptosis properties with high safety.Frondoside A, a natural glycoside extracted from the sea cucumber, Cucumaria frondosa,
In vitro
Frondoside A (0-5 μM, 24 hours)causes concentration-dependent reduction in viability of lung and breast cancer cells through a caspase 3/7-dependent cell death pathway.
In vivo
Frondoside A (0.01 and 1 mg/kg/ day i.p. for 25 days) significantly decreases the growth, the lymph node metastasis?and angiogenesis of LNM35 tumor xenografts in mice, without obvious toxic side-effects.
Chemical Properties
Molecular Weight1336.45
FormulaC60H96NaO29S
Cas No.127367-76-4
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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