Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty

gamma-DGG

gamma-DGG
gamma-DGG is a competitive blocker of AMPA receptor.
Catalog No. T15369Cas No. 6729-55-1

Resource Download

gamma-DGG

Catalog No. T15369Alias γ-D-Glutamylglycine, γDGGCas No. 6729-55-1

gamma-DGG is a competitive blocker of AMPA receptor.
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.
Pack SizePriceAvailabilityQuantity
5 mg$397-10 days
10 mg$557-10 days
Bulk & Custom
Add to Cart

Product Introduction

Bioactivity
Description
gamma-DGG is a competitive blocker of AMPA receptor.
In vitro
gamma-DGG (γ-DGG) is the most effective antagonist of the excitatory postsynaptic potentials (e.p.s.p.s). Its action is reversible and not associated with any change in the passive membrane properties of the granule cells or in the apparent reversal potential of the e.p.s.p.gamma-DGG blocks less at higher glutamate concentration. gamma-DGG (200-400 μM) in the bath decreases the miniature EPSC (mEPSC) amplitude by 26±2% (n=5 synapses) and shifts both the mEPSC amplitude distribution and the cumulative probability curve to the left [1]. The quantal analysis displays that the reduction in the e.p.s.p. paralleled the reduction in quantal size rather than quantal content, confirming a post-synaptic site of the action of gamma-DGG [2].
Aliasγ-D-Glutamylglycine, γDGG
Chemical Properties
Molecular Weight204.18
FormulaC7H12N2O5
Cas No.6729-55-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
H2O: 150 mg/mL (734.65 mM)
Solution Preparation Table
H2O
1mg5mg10mg50mg
1 mM4.8976 mL24.4882 mL48.9764 mL244.8820 mL
5 mM0.9795 mL4.8976 mL9.7953 mL48.9764 mL
10 mM0.4898 mL2.4488 mL4.8976 mL24.4882 mL
20 mM0.2449 mL1.2244 mL2.4488 mL12.2441 mL
50 mM0.0980 mL0.4898 mL0.9795 mL4.8976 mL
100 mM0.0490 mL0.2449 mL0.4898 mL2.4488 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Related Tags: buy gamma-DGG | purchase gamma-DGG | gamma-DGG cost | order gamma-DGG | gamma-DGG chemical structure | gamma-DGG in vitro | gamma-DGG formula | gamma-DGG molecular weight