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GC 14 is a selective thyroid hormone receptor antagonist with IC50 values of 200 nM for hTRα and 35 nM for hTRβ.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $2,270 | 3-6 months | |
50 mg | $2,980 | 3-6 months | |
100 mg | $4,000 | 3-6 months |
Description | GC 14 is a selective thyroid hormone receptor antagonist with IC50 values of 200 nM for hTRα and 35 nM for hTRβ. |
Targets&IC50 | TRα (human):200 nM , TRβ (human):35 nM |
In vitro | GC 14 exhibits structural modifications, including extensions at the 5′-position of the external thyronine ring or from the connecting carbon. Despite these alterations, it demonstrates only modest affinity and efficacy towards the thyroid hormone receptor (TR). |
Molecular Weight | 449.5 |
Formula | C26H27NO6 |
Cas No. | 447415-34-1 |
Relative Density. | 1.241 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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