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GDI2-IN-1 (compound (+)-37), a GDP-dissociation inhibitor beta (GDI2) inhibitor, demonstrates potent inhibitory activity with an IC50 of 2.87 μM and a K D of 36 μM, and exhibits excellent in vivo antitumor efficacy in pancreatic xenograft models overexpressing GDI2 [1].
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Description | GDI2-IN-1 (compound (+)-37), a GDP-dissociation inhibitor beta (GDI2) inhibitor, demonstrates potent inhibitory activity with an IC50 of 2.87 μM and a K D of 36 μM, and exhibits excellent in vivo antitumor efficacy in pancreatic xenograft models overexpressing GDI2 [1]. |
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