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Gefapixant-d3

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Catalog No. TMIH-0250

Gefapixant-d3 is a deuterated compound of Gefapixant. Gefapixant has a CAS number of 1015787-98-0. Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.

Gefapixant-d3
Other Forms of Gefapixant-d3:

Gefapixant-d3

😃Good
Catalog No. TMIH-0250
Gefapixant-d3 is a deuterated compound of Gefapixant. Gefapixant has a CAS number of 1015787-98-0. Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Pack SizePriceAvailabilityQuantity
1 mg$4577-10 days
5 mg$1,3707-10 days
10 mg$2,2807-10 days
25 mg$4,2207-10 days
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Product Introduction

Bioactivity
Description
Gefapixant-d3 is a deuterated compound of Gefapixant. Gefapixant has a CAS number of 1015787-98-0. Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors.
Chemical Properties
Molecular Weight356.42
FormulaC14H16D3N5O4S
Storage & Solubility Information
StorageShipping with blue ice.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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