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Glutamate-5-kinase-IN-2

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Catalog No. T60645

Glutamate-5-kinase-IN-2 (compound 54) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC of 4.2 μM, exhibiting G5K inhibition by promoting conformational changes at the L-glutamate binding site. Glutamate-5-kinase-IN-2 has potential for anti-TB research [1].

Glutamate-5-kinase-IN-2

Glutamate-5-kinase-IN-2

😃Good
Catalog No. T60645
Glutamate-5-kinase-IN-2 (compound 54) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC of 4.2 μM, exhibiting G5K inhibition by promoting conformational changes at the L-glutamate binding site. Glutamate-5-kinase-IN-2 has potential for anti-TB research [1].
Pack SizePriceAvailabilityQuantity
25 mg$1,52010-14 weeks
50 mg$1,98010-14 weeks
100 mg$2,50010-14 weeks
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Product Introduction

Bioactivity
Description
Glutamate-5-kinase-IN-2 (compound 54) is a potent glutamate-5-kinase (G5K) inhibitor with an MIC of 4.2 μM, exhibiting G5K inhibition by promoting conformational changes at the L-glutamate binding site. Glutamate-5-kinase-IN-2 has potential for anti-TB research [1].
In vitro
Glutamate-5-kinase-IN-2 (compound 54) (40 μM) inhibits G5K activity with an IC50 of 33 μM at 10 mM concentrations of L-Glu and ATP [1]. Additionally, Glutamate-5-kinase-IN-2 (5, 10, 20 μM) exhibits no significant cytotoxicity in HepG2 cells [1].
Chemical Properties
Molecular Weight296.73
FormulaC17H10ClFN2
Storage & Solubility Information
StorageShipping with blue ice.

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