Popular Searches
Diphenyleneiodonium chlorideEpacadostatGilteritinibDinaciclibRo-3306
TargetMol | Star Product
Wikimole
TargetMol | New Product
New Product
TargetMol | Compound Library
Compound Library
Contact Us
Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
TOPBioactivityChemical infoStorage&SolubilityCalculator

Gly-Arg-AMC (hydrochloride)

😃Good
Catalog No. T35932Cas No. 70274-78-1

Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.

Gly-Arg-AMC (hydrochloride)

Gly-Arg-AMC (hydrochloride)

😃Good
Catalog No. T35932Cas No. 70274-78-1
Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
Pack SizePriceAvailabilityQuantity
1 mg$93 35 days
5 mg$394 35 days
10 mg$693 35 days
25 mg$1,540 35 days
Bulk & Custom
Add to Cart
Questions
View More
Contact us for more batch information
Resource Download
All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity
Description
Gly-Arg-AMC is a fluorogenic substrate for cathepsin C.1 Upon enzymatic cleavage by cathepsin C, 7-amino-4-methylcoumarin (AMC) is released and its fluorescence can be used to quantify cathepsin C activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively.
|1. Rubach, J.K., Cui, G., Schneck, J.L., et al. The amino-acid substituents of dipeptide substrates of cathepsin C can determine the rate-limiting steps of catalysis. Biochemistry 51(38), 7551-7568 (2012).
Chemical Properties
Molecular Weight424.89
FormulaC18H25ClN6O4
Cas No.70274-78-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO:PBS (pH 7.2) (1:1): 0.5 mg/mL (1.18 mM), Sonication is recommended.
DMSO: 30 mg/mL (70.61 mM), Sonication is recommended.
Ethanol: 20 mg/mL (47.07 mM), Sonication is recommended.
DMF: 30 mg/mL (70.61 mM), Sonication is recommended.
Solution Preparation Table
Ethanol/DMSO/DMF
1mg5mg10mg50mg
5 mM0.4707 mL2.3536 mL4.7071 mL23.5355 mL
10 mM0.2354 mL1.1768 mL2.3536 mL11.7678 mL
20 mM0.1177 mL0.5884 mL1.1768 mL5.8839 mL
DMSO/DMF
1mg5mg10mg50mg
50 mM0.0471 mL0.2354 mL0.4707 mL2.3536 mL

Calculator

  • Molarity Calculator
  • Dilution Calculator
  • Reconstitution Calculator
  • Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
1 Enter information below:
mg/kg
g
μL
2 Enter the in vivo formulation:
% DMSO
%
%Tween 80
%ddH2O

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Gly-Arg-AMCGly Arg AMC (hydrochloride)GlyArgAMC (hydrochloride)
Related Tags: buy Gly-Arg-AMC (hydrochloride) | purchase Gly-Arg-AMC (hydrochloride) | Gly-Arg-AMC (hydrochloride) cost | order Gly-Arg-AMC (hydrochloride) | Gly-Arg-AMC (hydrochloride) chemical structure | Gly-Arg-AMC (hydrochloride) formula | Gly-Arg-AMC (hydrochloride) molecular weight
TargetMol | Logo

Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.