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Gochnatiolide A is a dimeric sesquiterpene derived from plants such as Ainsliaea henryi, exhibiting significant antiproliferative activity against various cancer cell lines, including renal, melanoma, ovarian-resistant, and glioma cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $498 | In Stock | |
5 mg | $1,245 | In Stock | |
10 mg | $1,643 | In Stock | |
25 mg | $2,793 | In Stock |
Description | Gochnatiolide A is a dimeric sesquiterpene derived from plants such as Ainsliaea henryi, exhibiting significant antiproliferative activity against various cancer cell lines, including renal, melanoma, ovarian-resistant, and glioma cells. |
In vitro | Methods: 786.0, UACC-62, NCI-ADR/RES, U251, MCF-7, NCI-H460, HT-29, PC-3, OVCAR-3, VERO and K562 cells were treated with Gochnatiolide A (0.25-250 μg/mL; 48 h) and their TGI (total growth inhibition) values were determined. Results: Gochnatiolide A inhibited cell growth with TGI (total growth inhibition) values of 0.42, 0.49, 0.70, 1.09, 1.69, 4.66, 5.42, 6.63, 54.73, 13.13 and 114.87 μg/mL for 786.0, UACC-62, NCI-ADR/RES, U251, MCF-7, NCI-H460, HT-29, PC-3, OVCAR-3, VERO and K562 cells, respectively. [1] |
Molecular Weight | 502.56 |
Formula | C30H30O7 |
Cas No. | 87606-12-0 |
Smiles | O=C1[C@@]2(C3=C4[C@](C(=C)C3=O)([C@@]5([C@@](CC[C@]4(O)CC2)(C(=C)C(=O)O5)[H])[H])[H])[C@@]6([C@@]7([C@](C(=C)C(=O)O7)(CCC(=C)[C@@]6(C1)[H])[H])[H])[H] |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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