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GoSlo-SR-5-69

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Catalog No. T37294Cas No. 1363419-31-1

BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).

GoSlo-SR-5-69

GoSlo-SR-5-69

😃Good
Catalog No. T37294Cas No. 1363419-31-1
BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).
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10 mg$79335 days
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Product Introduction

Bioactivity
Description
BK channel activator (EC50 = 251 nM). Shifts the voltage required for half maximal negatively (DV1/2 = -104 mV).
Chemical Properties
Molecular Weight471.48
FormulaC24H20N2NaO5S
Cas No.1363419-31-1
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 47.05 mg/mL (100 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM2.1210 mL10.6049 mL21.2098 mL106.0490 mL
5 mM0.4242 mL2.1210 mL4.2420 mL21.2098 mL
10 mM0.2121 mL1.0605 mL2.1210 mL10.6049 mL
20 mM0.1060 mL0.5302 mL1.0605 mL5.3025 mL
50 mM0.0424 mL0.2121 mL0.4242 mL2.1210 mL
100 mM0.0212 mL0.1060 mL0.2121 mL1.0605 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Dose Conversion

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