Shopping Cart
- Remove All
Your shopping cart is currently empty
GRP-60367 hydrochloride
😃Good
Catalog No. T61763
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1].
GRP-60367 hydrochloride
GRP-60367 hydrochloride
😃Good
Catalog No. T61763
GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 500 mg | $1,690 | 1-2 weeks |
Bulk & Custom
Add to Cart
Questions
View MoreContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | GRP-60367 hydrochloride is a novel small-molecule entry inhibitor of rabies virus (RABV), exhibiting nanomolar potency against select RABV strains. This first-in-class compound effectively targets the RABV G protein [1]. |
| In vitro | GRP-60367, ranging in concentration from 0.1 nM to 1000 μM, demonstrates specific and potent activity against RABV, achieving EC50 values between 2 and 52 nM across different host cell lines (BEAS-2B, 293T, Hep-2) in dose-response assays. The cell viability assays, conducted over 48 hours with concentrations from 0.1 nM to 1000 μM, yielded EC50s of 2 nM, 3 nM, and 52 nM for the RABV-ΔG-nanoLuc virus in BEAS-2B, 293T, and Hep-2 cell lines, respectively. |
| Molecular Weight | 389.92 |
| Formula | C21H28ClN3O2 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy GRP-60367 hydrochloride | purchase GRP-60367 hydrochloride | GRP-60367 hydrochloride cost | order GRP-60367 hydrochloride | GRP-60367 hydrochloride in vitro | GRP-60367 hydrochloride formula | GRP-60367 hydrochloride molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.