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GSK-3/CDK5/CDK2-IN-1

Name: GSK-3/CDK5/CDK2-IN-1
Brand: TargetMol
SKU: T35555
Price: 43 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T35555Cas No. 395074-72-3

Alias GSK-3/CDK5/CDK2-IN-1

GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].

GSK-3/CDK5/CDK2-IN-1

🥰Excellent

Catalog No. T35555Alias GSK-3/CDK5/CDK2-IN-1Cas No. 395074-72-3

GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].

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Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1].
In vitro	GSK-3/CDK5/CDK2-IN-1 inhibits CDK5 peptide substrate phosphorylation with an IC50 of less than 50 μM[1].
Alias	GSK-3/CDK5/CDK2-IN-1

Chemical Properties

Molecular Weight	362.433
Formula	C₂₁H₂₂N₄O₂
Cas No.	395074-72-3
Relative Density.	1.31 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 100 mg/mL (275.92 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7591 mL	13.7957 mL	27.5913 mL	137.9565 mL
5 mM	0.5518 mL	2.7591 mL	5.5183 mL	27.5913 mL
10 mM	0.2759 mL	1.3796 mL	2.7591 mL	13.7957 mL
20 mM	0.1380 mL	0.6898 mL	1.3796 mL	6.8978 mL
50 mM	0.0552 mL	0.2759 mL	0.5518 mL	2.7591 mL
100 mM	0.0276 mL	0.1380 mL	0.2759 mL	1.3796 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

GSK3/CDK5/CDK2IN1GSK-3/CDK-5/CDK2-IN-1GSK 3/CDK5/CDK2 IN 1