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GSK1842799 HCl

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Catalog No. T71069Cas No. 1277165-15-7

GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000× selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK/PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical.

GSK1842799 HCl

GSK1842799 HCl

😃Good
Catalog No. T71069Cas No. 1277165-15-7
GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000× selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK/PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical.
Pack SizePriceAvailabilityQuantity
25 mg1.729 €8-10 weeks
50 mg2.261 €8-10 weeks
100 mg2.945 €8-10 weeks
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Product Introduction

Bioactivity
Description
GSK1842799 is a selective S1P1 receptor agonist for multiple sclerosis. Upon phosphorylation, GSK1842799 showed subnanomole S1P1 agonist activity with >1000× selectivity over S1P3. GSK1842799 demonstrated good oral bioavailability. On the basis of the favorable in vitro ADME and in vivo PK/PD properties as well as broad toxicology evaluations, GSK1842799 was selected as a candidate for further clinical.
Chemical Properties
Molecular Weight504.4342
FormulaC20H30Cl2F3N3O2S
Cas No.1277165-15-7
Storage & Solubility Information
StorageShipping with blue ice.

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