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GTPγS tetralithium

Name: GTPγS tetralithium
Brand: TargetMol
SKU: T82252
Price: 369 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T82252Cas No. 94825-44-2

Alias Guanosine 5'-[γ-thio]triphosphate tetralithium

GTPγS tetralithium (Guanosine 5'-[γ-thio]triphosphate tetralithium) is a G-protein activator, a non-hydrolyzable GTP analog that protects proteins from proteolytic degradation.GTPγS tetralithium is involved in the detection of cells expressing recombinant receptors and endogenous receptors. GTPγS tetralithium is involved in the detection of GPCR signaling in cells expressing recombinant receptors as well as in cells and tissues expressing endogenous receptors, and can be assayed to measure agonist-induced desensitization of two human polymorphic α2B-adrenoceptor variants.

GTPγS tetralithium

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Catalog No. T82252Alias Guanosine 5'-[γ-thio]triphosphate tetralithiumCas No. 94825-44-2

Pack Size	Price	Availability	Quantity
1 mg	$369	In Stock
5 mg	$829	35 days

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Product Introduction

Bioactivity

Description

Alias

Guanosine 5'-[γ-thio]triphosphate tetralithium

Chemical Properties

Molecular Weight	562.98
Formula	C₁₀H₁₂Li₄N₅O₁₃P₃S
Cas No.	94825-44-2
Smiles	O[C@H]1[C@@H](O[C@@H]([C@H]1O)COP(OP(OP([O-])([S-])=O)([O-])=O)([O-])=O)N2C3=C(C(N=C(N3)N)=O)N=C2.[Li+].[Li+].[Li+].[Li+]

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

H2O: 80 mg/mL (142.10 mM)

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.7763 mL	8.8813 mL	17.7626 mL	88.8131 mL
5 mM	0.3553 mL	1.7763 mL	3.5525 mL	17.7626 mL
10 mM	0.1776 mL	0.8881 mL	1.7763 mL	8.8813 mL
20 mM	0.0888 mL	0.4441 mL	0.8881 mL	4.4407 mL
50 mM	0.0355 mL	0.1776 mL	0.3553 mL	1.7763 mL
100 mM	0.0178 mL	0.0888 mL	0.1776 mL	0.8881 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc