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H100

Catalog No. T11528Cas No. 643727-55-3

H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.

H100

H100

Catalog No. T11528Cas No. 643727-55-3
H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.
Pack SizePriceAvailabilityQuantity
25 mg$1,5206-8 weeks
50 mg$1,9806-8 weeks
100 mg$2,5006-8 weeks
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Product Introduction

Bioactivity
Description
H100 is a Cl- transport inhibitor, no effect against KCl cotransporter. It has partial effects against both the NaK2Cl cotransporter and the Band 3 anion exchanger.
In vitro
H100 (0.1 mM) demonstrates significant inhibitory activity on chloride transport in human erythrocytes, with 63% and 74% inhibition of the NaK2Cl cotransporter (NKCC) and the Band 3 anion exchanger (AE), respectively. It acts as a Cl- transport inhibitor, selectively targeting NKCC and AE without affecting the KCl cotransporter (KCC).
Chemical Properties
Molecular Weight388.4
FormulaC18H16N2O6S
Cas No.643727-55-3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Keywords

H 100H100H-100
Related Tags: buy H100 | purchase H100 | H100 cost | order H100 | H100 chemical structure | H100 in vitro | H100 formula | H100 molecular weight
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