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H2N-PEG4-Hydrazide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells.
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500 mg | Inquiry | Backorder |
Description | H2N-PEG4-Hydrazide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands joined by a linker: one ligand binds to an E3 ubiquitin ligase, and the other targets a specific protein. By utilizing the intracellular ubiquitin-proteasome system, PROTACs enable the selective degradation of target proteins [1]. |
Molecular Weight | 279.33 |
Formula | C11H25N3O5 |
Cas No. | 1425973-15-4 |
Relative Density. | 1.122 g/cm3 (Predicted) |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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