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H2N-PEG8-Hydrazide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | H2N-PEG8-Hydrazide is a PEG-based linker for PROTACs that joins two essential ligands, crucial for forming PROTAC molecules, enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one targeting an E3 ubiquitin ligase and the other the target protein. By utilizing the intracellular ubiquitin-proteasome system, PROTACs selectively degrade target proteins[1]. |
Molecular Weight | 455.54 |
Formula | C19H41N3O9 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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