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hAChE-IN-2

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Catalog No. T78692

hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1].

hAChE-IN-2

hAChE-IN-2

😃Good
Catalog No. T78692
hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1].
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Product Introduction

Bioactivity
Description
hAChE-IN-2, a potent inhibitor of human acetylcholinesterase (hAChE), exhibits an inhibitory concentration 50 (IC50) of 0.71 μM and additionally impedes tau-oligomerization with an effective concentration 50 (EC50) of 2.21 μM, demonstrating neuroprotective activity [1].
Targets&IC50
AChE (human):0.71 μM
In vitro
Compound 21 (hAChE-IN-2), at concentrations ranging from 1-10 μM, exhibited neuroprotective activity in SH-SY5Y cells transfected with wild-type tau [1].
Chemical Properties
Molecular Weight394.44
FormulaC22H23FN4O2
Storage & Solubility Information
StorageShipping with blue ice.

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