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Halofantrine hydrochloride

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Catalog No. T15460Cas No. 36167-63-2
Alias WR-171669, SKF-102886

Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent.

Halofantrine hydrochloride

Halofantrine hydrochloride

🥰Excellent
Catalog No. T15460Alias WR-171669, SKF-102886Cas No. 36167-63-2
Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent.
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Product Introduction

Bioactivity
Description
Halofantrine hydrochloride is a blocker of delayed rectifier potassium current. Halofantrine hydrochloride also via the inhibition of the human-ether-a-go-go-related gene (HERG) channel and a potent antimalarial agent.
AliasWR-171669, SKF-102886
Chemical Properties
Molecular Weight536.89
FormulaC26H31Cl3F3NO
Cas No.36167-63-2
Relative Density.1.31g/cm3
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 30 mg/mL (55.88 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.8626 mL9.3129 mL18.6258 mL93.1289 mL
5 mM0.3725 mL1.8626 mL3.7252 mL18.6258 mL
10 mM0.1863 mL0.9313 mL1.8626 mL9.3129 mL
20 mM0.0931 mL0.4656 mL0.9313 mL4.6564 mL
50 mM0.0373 mL0.1863 mL0.3725 mL1.8626 mL

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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