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hCA/Wnt/β-catenin-IN-1 (Compd 15) is an inhibitor selectively targeting hCA isoforms II, IX, and XII, with K i values of 33.6, 24.1, and 6.8 nM, respectively. It also attenuates P-gp activity, disrupts the Wnt/β-catenin signaling pathway, and compromises the viability of cancer cells, specifically against the NCI/ADR-RES DOX-resistant cell line [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
5 mg | Inquiry | Backorder | |
50 mg | Inquiry | Backorder |
Description | hCA/Wnt/β-catenin-IN-1 (Compd 15) is an inhibitor selectively targeting hCA isoforms II, IX, and XII, with K i values of 33.6, 24.1, and 6.8 nM, respectively. It also attenuates P-gp activity, disrupts the Wnt/β-catenin signaling pathway, and compromises the viability of cancer cells, specifically against the NCI/ADR-RES DOX-resistant cell line [1]. |
Storage | Shipping with blue ice. |
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