Shopping Cart
- Remove All
![TargetMol](https://www.targetmol.com/storage/error/oops.webp)
Your shopping cart is currently empty
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 6-8 weeks | |
50 mg | $1,980 | 6-8 weeks | |
100 mg | $2,500 | 6-8 weeks |
Description | hCAIX-IN-8 (compound 7i) is a highly potent and selective inhibitor of hCAIX, demonstrating potent inhibitory activity against CAIX with an IC50 value of 0.024 μM. It also exhibits inhibitory activity against CAII and CAVA with IC50 values of 1.99 μM and 1.10 μM, respectively. Furthermore, hCAIX-IN-8 exhibits anti-proliferative effects and low toxicity. It effectively reduces the occurrence of epithelial-to-mesenchymal transitions and promotes apoptosis. Additionally, hCAIX-IN-8 effectively inhibits cell migration and colonization potential [1]. |
In vitro | hCAIX-IN-8 (compound 7i) shows anti-proliferation activity with IC 50 是of 8.44, 11.22 μM for HT29, HepG2 cells, respectively [1]. hCAIX-IN-8 induces apoptosis in 24.44% and 19.22% of HT29 and HepG2 cells, respectivelysup>[1]. |
Molecular Weight | 396.35 |
Formula | C19H16N4O6 |
Cas No. | 2414633-40-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Copyright © 2015-2024 TargetMol Chemicals Inc. All Rights Reserved.