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HDAC3/6-IN-2

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Catalog No. T74003Cas No. 2417510-17-7

HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, with IC50 values of 0.368 μM and 0.635 μM, respectively. This compound demonstrates antitumor effects by inducing apoptosis in cancer cells, reducing HDAC6 and HDAC3 levels, and increasing acetylation of H3 and α-tubulin [1].

HDAC3/6-IN-2

HDAC3/6-IN-2

😃Good
Catalog No. T74003Cas No. 2417510-17-7
HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, with IC50 values of 0.368 μM and 0.635 μM, respectively. This compound demonstrates antitumor effects by inducing apoptosis in cancer cells, reducing HDAC6 and HDAC3 levels, and increasing acetylation of H3 and α-tubulin [1].
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Product Introduction

Bioactivity
Description
HDAC3/6-IN-2 (compound 15) is a dual inhibitor targeting HDAC6 and HDAC3, with IC50 values of 0.368 μM and 0.635 μM, respectively. This compound demonstrates antitumor effects by inducing apoptosis in cancer cells, reducing HDAC6 and HDAC3 levels, and increasing acetylation of H3 and α-tubulin [1].
Chemical Properties
Molecular Weight822.09
FormulaC49H67N5O6
Cas No.2417510-17-7
Storage & Solubility Information
StorageShipping with blue ice.

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