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Heishuixiecaoline A

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Catalog No. TN1726Cas No. 1469493-85-3

Heishuixiecaoline A protects against neurotoxicity in PC12 cells.

Heishuixiecaoline A

Heishuixiecaoline A

😃Good
Catalog No. TN1726Cas No. 1469493-85-3
Heishuixiecaoline A protects against neurotoxicity in PC12 cells.
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Product Introduction

Bioactivity
Description
Heishuixiecaoline A protects against neurotoxicity in PC12 cells.
In vitro
Three new germacrane-type sesquiterpenoids, Heishuixiecaoline A, heishuixiecaoline B, heishuixiecaoline C (compounds 1-3), were isolated along with ten known compounds 4-13 from fraction of Valeriana amurensis roots and rhizomes effective against Alzheimer's disease (AD). The structures of 1-3 were elucidated on the basis of their spectroscopic data. We also investigated the protective effect of compounds 1-13 on the neurotoxicity of PC12 cells induced by amyloid-beta (Aβ(25-25)), respectively.
Chemical Properties
Molecular Weight276.37
FormulaC17H24O3
Cas No.1469493-85-3
Relative Density.1.06 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
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Heishuixiecaoline A
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