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Hemopressin(rat) TFA
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Catalog No. T75798Cas No. 1431329-47-3
Hemopressin(rat) TFA, a nonapeptide originating from the α1-chain of hemoglobin, was first isolated from rat brain homogenates. It acts as an orally active, selective, and inverse agonist of the CB1 cannabinoid receptors and demonstrates antinociceptive effects in models of inflammatory pain [1] [2].
Hemopressin(rat) TFA
Hemopressin(rat) TFA
😃Good
Catalog No. T75798Cas No. 1431329-47-3
Hemopressin(rat) TFA, a nonapeptide originating from the α1-chain of hemoglobin, was first isolated from rat brain homogenates. It acts as an orally active, selective, and inverse agonist of the CB1 cannabinoid receptors and demonstrates antinociceptive effects in models of inflammatory pain [1] [2].
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 5 mg | Inquiry | 8-10 weeks | |
| 50 mg | Inquiry | 8-10 weeks |
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Chemical Properties
| Description | Hemopressin(rat) TFA, a nonapeptide originating from the α1-chain of hemoglobin, was first isolated from rat brain homogenates. It acts as an orally active, selective, and inverse agonist of the CB1 cannabinoid receptors and demonstrates antinociceptive effects in models of inflammatory pain [1] [2]. |
| In vivo | Hemopressin(rat) TFA induces hypotension in anesthetized rats, undergoing metabolism by endopeptidase 24.15 (EP24.15), neurolysin (EP24.16), and angiotensin-converting enzyme (ACE) [1]. When administered orally, it mitigates mechanical hyperalgesia in CCI-rats for up to 6 hours. Additionally, treatment with Hemopressin(rat) TFA reduces Egr-1 immunoreactivity (Egr-1Ir) in the spinal cord's superficial dorsal horn of CCI rats [2]. |
| Molecular Weight | 1202.28 |
| Formula | C55H78F3N13O14 |
| Cas No. | 1431329-47-3 |
Storage & Solubility Information
| Storage | Shipping with blue ice. |
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DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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