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Heptaethylene glycol is a PEG-based linker for PROTACs, joining two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | 7-10 days | |
500 mg | Inquiry | 7-10 days |
Description | Heptaethylene glycol is a PEG-based linker for PROTACs, joining two essential ligands necessary for PROTAC molecule formation. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs comprise two distinct ligands linked by a connector: one ligand targets an E3 ubiquitin ligase and the other targets the desired protein. PROTACs leverage the ubiquitin-proteasome system within cells to selectively degrade target proteins[1]. |
Alias | HO-PEG7-OH |
Molecular Weight | 326.38 |
Formula | C14H30O8 |
Cas No. | 5617-32-3 |
Relative Density. | 1.31g/cm3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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