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Description | HO-PEG17-OH is a PEG-based linker for PROTACs, joining two essential ligands that are crucial for forming PROTAC molecules, and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs, composed of two ligands linked together—one binding to an E3 ubiquitin ligase and the other to the target protein—utilize the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 766.91 |
Formula | C34H70O18 |
Cas No. | 351342-04-6 |
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