Shopping Cart

Remove All
Your shopping cart is currently empty

HOKU-81

Name: HOKU-81
Brand: TargetMol
SKU: T15498
Price: 135 USD
Availability: InStock
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T15498Cas No. 58020-43-2

Alias 4-Hydroxytulobuterol

HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.

HOKU-81

🥰Excellent

Catalog No. T15498Alias 4-HydroxytulobuterolCas No. 58020-43-2

HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.

Product information is being updated, if you want to purchase, please click the bulk custom button.

Bulk & Custom

Questions

Resource Download

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.
In vitro	HOKU-81 was approximately 8 times more potent than tulobuterol, approximately twice as potent as salbutamol, and approximately as potent as isoprenaline in relaxing effect on the isolated tracheal smooth muscle preparation of guinea pigs. HOKU-81 appears to be a potent and selective beta 2-stimulant with a slight inotropic action. Adrenergic Receptor Effects of HOKU-81 on isolated trachea and atria of guinea pigs were compared with those of various bronchodilators. This effect of HOKU-81 seems to be due to direct action on the adrenergic beta-receptor.
Alias	4-Hydroxytulobuterol

Chemical Properties

Molecular Weight	243.73
Formula	C₁₂H₁₈ClNO₂
Cas No.	58020-43-2
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 50 mg/mL (205.15 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.1029 mL	20.5145 mL	41.0290 mL	205.1450 mL
5 mM	0.8206 mL	4.1029 mL	8.2058 mL	41.0290 mL
10 mM	0.4103 mL	2.0515 mL	4.1029 mL	20.5145 mL
20 mM	0.2051 mL	1.0257 mL	2.0515 mL	10.2573 mL
50 mM	0.0821 mL	0.4103 mL	0.8206 mL	4.1029 mL
100 mM	0.0410 mL	0.2051 mL	0.4103 mL	2.0515 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

HOKU81HOKU-81HOKU 81