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hu14.18 (K322A)

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Catalog No. T9901A-481

hu14.18 (K322A) is a humanized monoclonal antibody targeting disialoganglioside GD2, comprised of a fully human amino acid sequence of immunoglobulin G1 heavy chain and κ light chain. This antibody exhibits antibody-dependent cellular cytotoxicity (ADCC) and is utilized in studying high-risk neuroblastoma.

hu14.18 (K322A)

hu14.18 (K322A)

😃Good
Catalog No. T9901A-481
hu14.18 (K322A) is a humanized monoclonal antibody targeting disialoganglioside GD2, comprised of a fully human amino acid sequence of immunoglobulin G1 heavy chain and κ light chain. This antibody exhibits antibody-dependent cellular cytotoxicity (ADCC) and is utilized in studying high-risk neuroblastoma.
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Product Introduction

Bioactivity
Description
hu14.18 (K322A) is a humanized monoclonal antibody targeting disialoganglioside GD2, comprised of a fully human amino acid sequence of immunoglobulin G1 heavy chain and κ light chain. This antibody exhibits antibody-dependent cellular cytotoxicity (ADCC) and is utilized in studying high-risk neuroblastoma.
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Storage & Solubility Information
Storagestore at low temperature | store at -20°C | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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