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HWL-088

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Catalog No. T11583Cas No. 2378617-96-8

HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.

HWL-088

HWL-088

😃Good
Catalog No. T11583Cas No. 2378617-96-8
HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.
Pack SizePriceAvailabilityQuantity
5 mg$3326-8 weeks
25 mg$1,0806-8 weeks
50 mg$1,4106-8 weeks
100 mg$1,9906-8 weeks
1 mL x 10 mM (in DMSO)$3336-8 weeks
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Product Introduction

Bioactivity
Description
HWL-088 is a potent free fatty acid receptor 1 (FFA1/GPR40) agonist. HWL-088 significantly improves glucose tolerance in normal and diabetic models.
Targets&IC50
PPARδ:570.9 nM (EC50), FFAR1/GPR40:18.9 nM (EC50)
Chemical Properties
Molecular Weight366.38
FormulaC22H19FO4
Cas No.2378617-96-8
Relative Density.1.241 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

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TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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Keywords

HWL 088HWL088HWL-088
Related Tags: buy HWL-088 | purchase HWL-088 | HWL-088 cost | order HWL-088 | HWL-088 chemical structure | HWL-088 formula | HWL-088 molecular weight
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