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Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Hydroxy-PEG2-CH2COOH is a PEG-based linker for PROTACs, facilitating the linkage of two essential ligands crucial for PROTAC molecule formation and enabling selective protein degradation via the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker; one ligand binds to an E3 ubiquitin ligase, while the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1]. |
Molecular Weight | 164.1565 |
Formula | C6H12O5 |
Cas No. | 51951-04-3 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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