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Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | Hydroxy-PEG8-CH2-Boc is a PEG-based linker for PROTACs that connects two essential ligands, crucial for PROTAC molecule formation, enabling selective protein degradation through the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two ligands connected by a linker: one targets an E3 ubiquitin ligase, while the other binds to the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins [1]. |
Alias | HO-PEG8-CH2COOtBu |
Molecular Weight | 484.58 |
Formula | C22H44O11 |
Cas No. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
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