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Hydroxystilbamidine bis(methanesulfonate)
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Catalog No. T19014Cas No. 223769-64-0
Hydroxystilbamidine bis(methanesulfonate) is a dye capable of binding to both DNA and RNA. It also is a potent inhibitor of cellular ribonucleases.
Hydroxystilbamidine bis(methanesulfonate)
😃Good
Catalog No. T19014Cas No. 223769-64-0
Hydroxystilbamidine bis(methanesulfonate) is a dye capable of binding to both DNA and RNA. It also is a potent inhibitor of cellular ribonucleases.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | $488 | 35 days |
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Product Introduction
Bioactivity
Chemical Properties
| Description | Hydroxystilbamidine bis(methanesulfonate) is a dye capable of binding to both DNA and RNA. It also is a potent inhibitor of cellular ribonucleases. |
| In vitro | The trypanocidal dye Hydroxystilbamidine bis(methanesulfonate) facilitates mRNA recovery following polysome release with Nonidet P-40 (NP-40), as analyzed by sucrose gradient distribution of detergent-lysed postnuclear supernates [1]. |
| In vivo | Hydroxystilbamidine bis(methanesulfonate) effectively inhibits the plaque-forming cell (PFC) response when administered prior to sheep erythrocytes (SRBC) stimulation. It reduces the plaque formation in treated mice, leading to a significant decrease in PFC levels. However, the suppressive effect diminishes over time, with PFC counts in both Hydroxystilbamidine bis(methanesulfonate)-treated and control groups reverting to baseline levels by day 14 [2]. |
| Molecular Weight | 472.53 |
| Formula | C18H24N4O7S2 |
| Cas No. | 223769-64-0 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
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Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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