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Pack Size | Price | Availability | Quantity |
---|---|---|---|
10 mg | $795 | 35 days | |
50 mg | $3,230 | 35 days |
Description | I-BET 151 dihydrochloride is a BET bromodomain inhibitor that prevents BET from recruiting to chromatin. |
In vitro | I-BET 151 induces MLL-fusion leukemia cell line apoptosis and G0 / G1 cell cycle arrest in vitro and reduces BCL2 expression in NOMO1 cells. |
In vivo | I-BET 151 improves the survival rate of two kinds of MLL fusion leukemia mice and enhances the differentiation of human iPSCs into megakaryocytes. |
Alias | I-BET 151 hydrochloride |
Molecular Weight | 488.37 |
Formula | C23H23Cl2N5O3 |
Cas No. | 1883545-47-8 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
Solubility Information | DMSO: Soluble |
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