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IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1].
Pack Size | Price | Availability | Quantity |
---|---|---|---|
25 mg | $1,520 | 10-14 weeks | |
50 mg | $1,980 | 10-14 weeks | |
100 mg | $2,500 | 10-14 weeks |
Description | IAA65 is a potent inhibitor of T-type calcium channels, exhibiting an IC50 value of 18.9 μM, and holds potential for use in epilepsy research [1]. |
In vitro | IAA65 at a concentration of 50 μM in differentiated ND7/23 cells notably decreases the current density produced through the activation of T-type Ca 2+ channels and modifies the steady-state inactivation of Cav3.2 and Cav3.3 T-type Ca 2+ channels. This modification significantly prolongs the channels' recovery time from inactivation [1]. |
Molecular Weight | 365.27 |
Formula | C16H13F6NO2 |
Cas No. | 2987139-96-6 |
Storage | Shipping with blue ice. |
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