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Ibrutinib Racemate

Name: Ibrutinib Racemate
Brand: TargetMol
SKU: T16440
Price: 64 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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Catalog No. T16440Cas No. 936563-87-0

Alias PCI-32765 (Racemate)

Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.

Ibrutinib Racemate

🥰Excellent

Catalog No. T16440Alias PCI-32765 (Racemate)Cas No. 936563-87-0

Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.

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COA

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Product Introduction

Bioactivity

Description	Ibrutinib is a selective, irreversible Btk inhibitor (IC50: 0.5 nM). Ibrutinib Racemate is the racemate of Ibrutinib.
Alias	PCI-32765 (Racemate)

Chemical Properties

Molecular Weight	440.5
Formula	C₂₅H₂₄N₆O₂
Cas No.	936563-87-0
Smiles	NC1=C2C(N(N=C2C3=CC=C(OC4=CC=CC=C4)C=C3)C5CN(C(C=C)=O)CCC5)=NC=N1
Relative Density.	1.34 g/cm3 (Predicted)

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 25 mg/mL (56.75 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2701 mL	11.3507 mL	22.7015 mL	113.5074 mL
5 mM	0.4540 mL	2.2701 mL	4.5403 mL	22.7015 mL
10 mM	0.2270 mL	1.1351 mL	2.2701 mL	11.3507 mL
20 mM	0.1135 mL	0.5675 mL	1.1351 mL	5.6754 mL
50 mM	0.0454 mL	0.2270 mL	0.4540 mL	2.2701 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

Ibrutinib RacematePCI32765RacematePCI 32765PCI-32765