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ELN318463 racemate
🥰Excellent
Catalog No. T11178LCas No. 851599-82-1
Alias ELN318463 (racemate), ELN 318463 racemate
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
ELN318463 racemate
🥰Excellent
Purity: 99.73%
Catalog No. T11178LAlias ELN318463 (racemate), ELN 318463 racemateCas No. 851599-82-1
ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 1 mg | $165 | In Stock | |
| 5 mg | $412 | In Stock | |
| 10 mg | $648 | In Stock | |
| 25 mg | $954 | In Stock | |
| 50 mg | $1,300 | In Stock | |
| 100 mg | $1,750 | In Stock | |
| 1 mL x 10 mM (in DMSO) | $471 | In Stock |
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CitedSelect Batch
Purity:99.73%
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All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.Product Introduction
Bioactivity
Chemical Properties
| Description | ELN318463 racemate (ELN 318463 racemate) is the racemate of ELN318463 which is an amyloid precursor protein (APP) selective γ-secretase inhibitor. |
| In vitro | ELN318463 shows differential inhibition of presenilin (PS1)- and PS2-comprised γ-secretase with EC50s of 12nM and 656 nM for PS1and PS2, respectively[1]. |
| In vivo | Brain levels of ELN318463 (30 mg/kg) are 0.754 μM in FVB brains and 0.69 μM, and of ELN318463(100 mg/kg) are 2.7 μM in FVB brains and 1.87 μM in PDAPP brains[1]. |
| Alias | ELN318463 (racemate), ELN 318463 racemate |
| Molecular Weight | 471.8 |
| Formula | C19H20BrClN2O3S |
| Cas No. | 851599-82-1 |
| Smiles | N(S(=O)(=O)C1=CC=C(Cl)C=C1)(CC2=CC=C(Br)C=C2)C3C(=O)NCCCC3 |
| Relative Density. | 1.56 g/cm3 (Predicted) |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
| Solubility Information | DMSO: 50 mg/mL (105.98 mM)  | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
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(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
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