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Tangeretin

Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notch-1 inhibitor.

Catalog No. T2842Cas No. 481-53-8

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Purity:99.37%

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COA LCMS HPLC HNMR

Tangeretin

Catalog No. T2842Cas No. 481-53-8

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Pack Size	Price	Availability
5 mg	$47	In Stock
10 mg	$85	In Stock
25 mg	$162	In Stock
50 mg	$311	In Stock
100 mg	$538	In Stock
1 mL x 10 mM (in DMSO)	$53	In Stock

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Product Introduction

Bioactivity

Description	Tangeretin (NSC-618905), a flavonoid from citrus fruit peels, has been proven to play an important role in anti-inflammatory responses and neuroprotective effects in several disease models and was also selected as a Notch-1 inhibitor.
In vitro	Tangeritin is a bitter tasting compound and can be found in a number of food items such as tea, sweet bay, garden onion (var. ), and broccoli. It has been proven to play an important role in neuroprotective effects and anti-inflammatory responses in several disease models and was also selected as a Notch-1 inhibitor.
Alias	NSC53909, Tangeritin, NSC618905

Chemical Properties

Molecular Weight	372.37
Formula	C₂₀H₂₀O₇
Cas No.	481-53-8

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.

Solubility Information

DMSO: 40 mg/mL (107.42 mM)

Methanol: 5 mg/mL (13.43 mM）, Sonication is recommended.

H2O: Insoluble

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

Solution Preparation Table

Methanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	2.6855 mL	13.4275 mL	26.8550 mL	134.2750 mL
5 mM	0.5371 mL	2.6855 mL	5.3710 mL	26.8550 mL
10 mM	0.2686 mL	1.3428 mL	2.6855 mL	13.4275 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.1343 mL	0.6714 mL	1.3428 mL	6.7138 mL
50 mM	0.0537 mL	0.2686 mL	0.5371 mL	2.6855 mL
100 mM	0.0269 mL	0.1343 mL	0.2686 mL	1.3428 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc