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IDT307 is a fluorescent analog of MPP+, a fluorescent substrate for DAT (fluorescent substrate APP+), and can be used for rapid identification and characterization of PMAT inhibitors.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
2 mg | $36 | In Stock | |
5 mg | $64 | In Stock | |
1 mL x 10 mM (in DMSO) | $54 | In Stock |
Description | IDT307 is a fluorescent analog of MPP+, a fluorescent substrate for DAT (fluorescent substrate APP+), and can be used for rapid identification and characterization of PMAT inhibitors. |
In vitro | IDT307 is an analog of the organic cation MPP+, which is transported to the parietal membrane (cerebrospinal fluid-facing side) of choroid plexus (CP) epithelial cells. Its transport process is highly sensitive to the PMAT inhibitor quinine. In Pmat knockout mice, uptake of IDT307 by choroid plexus tissue and its intracellular accumulation are significantly reduced by approximately 70%. [1] |
Alias | IDT 307 |
Molecular Weight | 340.2 |
Formula | C14H17IN2 |
Cas No. | 1141-41-9 |
Smiles | [I-].C=1C=C(C=CC1C=2C=C[N+](=CC2)C)N(C)C |
Relative Density. | no data available |
Storage | keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
Solubility Information | DMSO: 50.00 mg/mL (146.97 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||||||||||||
DMSO
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