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IgG light chain variable region [Homo sapiens]/IgM/kappa antibody [Mus musculus]

Catalog No. T22856

IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral) immunity before there is sufficient IgG. The immunoglobulin light chain is the small polypeptide subunit of an antibody ( immunoglobulin). Kappa (κ) chain, one of the two types of light chain in mammals, is encoded by the immunoglobulin kappa locus (IGK@) on chromosome 2. Only V and J segments are found in Ig light chains.

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Pack Size	Price	Availability
1 mg	$50	Backorder
5 mg	$143	Backorder
10 mg	$235	Backorder
25 mg	$329	Backorder

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Product Introduction

Bioactivity

Description	IgG has four forms, provides the majority of antibody-based immunity against invading pathogens. The only antibody capable of crossing the placenta to give passive immunity to the fetus. Eliminates pathogens in the early stages of B cell-mediated (humoral
In vitro	Increased levels of free Ig light chains have also been detected in various inflammatory diseases. Very recent studies have shown that Ig light chains not only activate mast cells but also dorsal root ganglia (Rijnierse, 2009)) and neutrophils (Braber and Thio (2012)), expanding their possible role as mediators in inflammatory disease.

Chemical Properties

Molecular Weight	809.9
Formula	C37H59N7O13
Cas No.

Storage & Solubility Information

Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year
Solubility Information	DMSO: ≥81mg/mL

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